4865-84-3, Name is 1,2-Benzisoxazole-3-acetic Acid, belongs to Benzisoxazole compound, is a common compound. HPLC of Formula: C9H7NO3In an article, once mentioned the new application about 4865-84-3.
Conventional & non conventional synthesis of biologically active novel pyrimidine and its moleculer descriptor study
3-Formylchromones 1 when treated with 2-(benzo[cf]isoxazol-3-yl) acetic acid 2 under microwave irradiation afforded 3-((E)-2-benzo[c/] isoxazol-3-yl) vinyl)-4H-chromen- 4-ones (3). Compounds 3 on treatment with thiourea gave the compound 5-(2- (benzo[d]isoxazol-3-yl) vinyl)-4(-2-hydroxypenyl) pyrimidine-2(1H)- Thiones 4. Compounds 3 on treatment with guanidine gave the compound 2-(5-(2- (benzol[dJisoxazol-3-yl)vinyl)-l,2-dihydro-2-iminopyrimidin-4- yl) phenols 5. Moleculer descriptor properties were analyzed by using simple moleculer descriptor used by “Lipinski’s rule of 5”. The structures of compounds were established on the basis of spectral data. Synthesized compounds were screened for their antimicrobial activities.
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Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics