Reference of 65685-50-9, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 65685-50-9, 5-Bromobenzo[d]isoxazol-3(2H)-one, introducing its new discovery.
Benzo[d]isoxazol-3-ol DAAO inhibitors
Methods for increasing D-Serine concentration and reducing concentration of the toxic products of D-Serine oxidation, for enhancing learning, memory and/or cognition, or for treating schizophrenia, Alzheimer”s disease, ataxia, or neuropathic pain, or preventing loss in neuronal function characteristic of neurodegenerative diseases involve administering to a subject in need of treatment a therapeutic amount of a compound of formula I, or a pharmaceutically acceptable salt or solvate thereof:
- Z1 is N or CR3;
- Z2 is N or CR4;
- Z3is O or S;
- A is hydrogen, alkyl or M+; M is aluminum, calcium, lithium, magnesium, potassium, sodium, zinc or a mixture thereof;
- R1, R2, R3 and R4 are independently selected from hydrogen, alkyl, hydroxy alkoxy, aryl, acyl, halo, cyano, haloalkyl, NHCOOR5 and SO2NH2;
- R5 is aryl, arylalkyl, heteroaryl or heteroarylalkyl;
- at least one of R1, R2, R3 and R4 is other than hydrogen; and
- at least one of Z1 and Z2 is other than N.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 65685-50-9, and how the biochemistry of the body works.Reference of 65685-50-9
Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics