Chemistry, like all the natural sciences, HPLC of Formula: C7H4BrNO2, begins with the direct observation of nature¡ª in this case, of matter. In a Article£¬Which mentioned a new discovery about 65685-50-9.
Synthesis and biological evaluation of D-amino acid oxidase inhibitors
D-Amino acid oxidase (DAAO) catalyzes the oxidation of D-amino acids including D-serine, a full agonist at the glycine site of the NMDA receptor. A series of benzo[d]isoxazol-3-ol derivatives were synthesized and evaluated as DAAO inhibitors. Among them, 5-chlorobenzo[d]isoxazol-3-ol (CBIO) potently inhibited DAAO with an IC50 in the submicromolar range. Oral administration of CBIO in conjunction with D-serine enhanced the plasma and brain levels of D-serine in rats compared to the oral administration of D-serine alone.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, HPLC of Formula: C7H4BrNO2, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about HPLC of Formula: C7H4BrNO2
Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics