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2-Bromo-2-nitropropane/Zn promoted reductive cyclizations of ortho-substituted nitroarenes toward 2,1-benzisoxazole derivatives
Under the mild conditions, reductive cyclizations of 2-nitrobenzaldehydes or 2′-nitroacetophenone towards 2,1-benzisoxazoles were accomplished in the presence of 2 bromo-2-nitropropane/Zn in methanolic solution. The synthetic utility and the role of 2-bromo-2-nitropropane were investigated.
If you are hungry for even more, make sure to check my other article about 546-89-4, Category: Benzisoxazole.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics