Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 79-14-1, Name is 2-Hydroxyacetic acid, molecular formula is , belongs to benzisoxazole compound. In a document, author is Hoy, Sheridan M., Recommanded Product: 79-14-1.
Zonisamide: A Review of Its Use as Adjunctive Therapy in the Management of Partial Seizures in Pediatric Patients Aged >= 6 Years
Oral zonisamide (Zonegran(A (R))) is a benzisoxazole derivative chemically unrelated to other antiepileptic drugs (AEDs). It is approved in the EU as an adjunct to other AEDs in the treatment of pediatric patients aged a parts per thousand yen6 years with partial seizures, with or without secondary generalization. In a randomized, double-blind, multinational, phase III study in pediatric patients aged 6-17 years with partial seizures, the proportion of patients achieving a a parts per thousand yen50 % reduction from baseline in seizure frequency per 28 days during the maintenance treatment period was significantly higher with adjunctive therapy with zonisamide than placebo. The antiepileptic efficacy of zonisamide was sustained during a 59-week extension study in this patient population. Zonisamide was generally well tolerated in these studies, with the majority of adverse events being mild or moderate in severity. Thus, oral zonisamide as an adjunctive therapy to other AEDs provides a useful option in the treatment of pediatric patients aged a parts per thousand yen6 years with partial seizures.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 79-14-1, in my other articles. Recommanded Product: 79-14-1.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics