Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 79-14-1, Name is 2-Hydroxyacetic acid, molecular formula is C2H4O3, Electric Literature of 79-14-1, belongs to benzisoxazole compound, is a common compound. In a patnet, author is Middleton, RJ, once mentioned the new application about 79-14-1.
A concise synthesis of novel homochiral aromatic amino acid surrogates comprising a tetrahydroindazole or a benzisoxazole system was developed via the acylation of a cyclic 1,3-diketone by the side-chain carboxyl functionality of either Boc-Asp-OtBu or Boc-Glu-OtBu followed by regioselective condensation with hydrazine, N-benzylhydrazine and hydroxylamine. The tetrahydroindazole nucleus was also constructed by the condensation of Boc-Asp-OtBu with the enamine, 1-pyrrolidino-1-cyclohexene followed by acid-hydrolytic treatment and reaction with hydrazines. Further functional group transformations gave N-alpha-Fmoc-protected derivatives as useful building blocks for solid-phase peptide assembly. (C) 2003 Elsevier Ltd. All rights reserved.
Electric Literature of 79-14-1, This is the end of this tutorial post, and I hope it has helped your research about 79-14-1.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics