In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Comparison of aromatic and aliphatic dicarboxylic acid in reactivity using hydrogen-isotope exchange reaction in a gas-solid system, published in 1994, which mentions a compound: 610-09-3, mainly applied to hydrogen exchange carboxylic acid kinetics; LFER hydrogen exchange carboxylic acid, Recommanded Product: 610-09-3.
The hydrogen-isotope exchange reaction between aromatic (alicyclic, or normal chain aliphatic) dicarboxylic acid (solid) and HTO vapor was observed at 40 °C ∼ 80° to reveal the reactivity of the material having the same two functional groups. The A””-McKay plot method was used to determine its rate constant From the rate constants thus determined, the following three findings have been clarified in the reaction. (1) The reactivity of aromatic dicarboxylic acid is similar to that of normal chain aliphatic dicarboxylic acid, and is greater than that of alicyclic acid. (2) With regard to 1,2- or 1,4-cyclohexanedicarboxylic acid, cis-isomer is similar to trans-isomer in reactivity. (3) The reactivity of isophthalic acid is larger than that of benzoic acid, and seems to follow the Hammett LFER.
This literature about this compound(610-09-3)Recommanded Product: 610-09-3has given us a lot of inspiration, and I hope that the research on this compound(cis-Cyclohexane-1,2-dicarboxylic acid) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics