In 1980,Acta Poloniae Pharmaceutica included an article by Domagalina, Eugenia; Gaj, Barbara; Slawik, Tomasz. Recommanded Product: 5-Bromobenzo[d]isoxazol-3(2H)-one. The article was titled 《Arylsulfonyl and sulfanilyl derivatives of benzoxazoles and benzisoxazoles》. The information in the text is summarized as follows:
Benzoxazoles I (R = Cl, Br, R1 = H; R = H, R1 = Cl, Br, SO2NH2; R = Cl, Br, R1 = SO2NH2) and benzisoxazoles II (R = H, Cl, Br, SO2NH2) were prepared in 33-74% yields by treating 2-benzoxazolinones or 3-hydroxybenzisoxazoles, resp., with 4-AcNHC6H4SO2Cl in dioxane containing some Et3N. Similarly, 5-, 6-, and 7-amino-2-benzoxazolinone yielded III. I and III were deacetylated with HCl-EtOH; under similar conditions II yielded sulfanilic acid and the starting benzisoxazole derivative After reading the article, we found that the author used 5-Bromobenzo[d]isoxazol-3(2H)-one(cas: 65685-50-9Recommanded Product: 5-Bromobenzo[d]isoxazol-3(2H)-one)
5-Bromobenzo[d]isoxazol-3(2H)-one(cas: 65685-50-9) belongs to benzisoxazole.Recommanded Product: 5-Bromobenzo[d]isoxazol-3(2H)-oneThe benzisoxazole analogs represent one of the privileged structures in medicinal chemistry and there has been an increasing number of studies on benzisoxazole-containing compounds. The unique benzisoxazole scaffold also exhibits an impressive potential as antimicrobial, anticancer, anti-inflammatory, anti-glycation agents and so on.
Referemce:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics