The author of 《Central effects of some new derivatives of benzoxazolin-2-one and 3-hydroxybenzisoxazole》 were Kolasa, Krystyna. And the article was published in Acta Poloniae Pharmaceutica in 1979. Recommanded Product: 65685-50-9 The author mentioned the following in the article:
The title compounds I (R = H or Br; R1 = H, Ac, or CO2Et), II (R = H or Br)and III (R = H or Br) tested in mice at their 1/5, 1/10, 1/20, and 1/40 LD50 dose showed a weak myorelaxant effect and weak inhibitory activity on the central nervous system. In the part of experimental materials, we found many familiar compounds, such as 5-Bromobenzo[d]isoxazol-3(2H)-one(cas: 65685-50-9Recommanded Product: 65685-50-9)
5-Bromobenzo[d]isoxazol-3(2H)-one(cas: 65685-50-9) belongs to benzisoxazole.The benzisoxazole analogs represent one of the privileged structures in medicinal chemistry and there has been an increasing number of studies on benzisoxazole-containing compounds. The unique benzisoxazole scaffold also exhibits an impressive potential as antimicrobial, anticancer, anti-inflammatory, anti-glycation agents and so on.Recommanded Product: 65685-50-9
Referemce:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics