Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Sakuma, Shogo, once mentioned the application of 929-59-9, Name is 1,2-Bis(2-aminoethoxy)ethane, molecular formula is C6H16N2O2, molecular weight is 148.2034, MDL number is MFCD00040474, category is Benzisoxazole. Now introduce a scientific discovery about this category, Recommanded Product: 1,2-Bis(2-aminoethoxy)ethane.
Biological evaluation of novel benzisoxazole derivatives as PPAR delta agonists
We discovered novel peroxisome proliferator-activated receptor delta agonists with a characteristic benzisoxazole ring. Compound 5 exhibited potent human PPAR delta transactivation activity. Furthermore, it stimulated the differentiation of oligodendrocyte precursor cells in vitro. This indicates that this potential drug may be effective for the treatment of demyelinating disorders such as multiple sclerosis. (C) 2011 Elsevier Ltd. All rights reserved.
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Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics