Chemistry is an experimental science, Category: Benzisoxazole, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 843666-40-0, Name is 18-(tert-Butoxy)-18-oxooctadecanoic acid, molecular formula is C22H42O4, belongs to benzisoxazole compound. In a document, author is Shantharam, C. S..
Inhibition of protein glycation by urea and thiourea derivatives of glycine/proline conjugated benzisoxazole analogue – Synthesis and structure-activity studies
Synthesis of a new series of urea/thiourea derivatives of Gly/Pro conjugated benzisoxazole has been reported. Structure of the compounds was characterized by physical and spectroscopical data and has been screened for their in vitro antiglycation activity. Several compounds showed promising activity with IC50 <5 mu M compared to standard rutin (IC50 = 41.9 mu M). Further, it was found that compounds containing methoxy and bromine substituents have exerted highly potent activity. Thus, the title compounds represent novel class of potent antiglycating agents. (C) 2012 Elsevier Masson SAS. All rights reserved. Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 843666-40-0. Category: Benzisoxazole.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics