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Condensation reactions of various nucleophiles with 3-formylchromone
3-Formylchromones 1 are condensed with 1-(2,4-difluorophenyl-2-[1,2,4] tnazol-4-yl)ethanone in acetic anhydride to afford 3-[3-(2,4-difluoro-phenyl)-3- oxo-2-[1,2,4]triazol-4-yl)propenyl]chromon-4-ones 2. 3-Formylchromone 1 when heated with benzo[d]isoxazol-3-yl-acetic acid in dry pyridine yield 3-(2-benzo[d]isoxazol-3-yl-vinyl)chromon-4-ones 3. Further, 3-formylchromone 1 on heating with N-methylpiperizine in ethanol give 1-(2-hydroxyphenyl)-3-(4- methyl-piperazin-1-yl)propenones 4.
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Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics