Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 4865-84-3, Name is 1,2-Benzisoxazole-3-acetic Acid,introducing its new discovery., HPLC of Formula: C9H7NO3
Conventional & non conventional synthesis of biologically active novel pyrimidine and its moleculer descriptor study
3-Formylchromones 1 when treated with 2-(benzo[cf]isoxazol-3-yl) acetic acid 2 under microwave irradiation afforded 3-((E)-2-benzo[c/] isoxazol-3-yl) vinyl)-4H-chromen- 4-ones (3). Compounds 3 on treatment with thiourea gave the compound 5-(2- (benzo[d]isoxazol-3-yl) vinyl)-4(-2-hydroxypenyl) pyrimidine-2(1H)- Thiones 4. Compounds 3 on treatment with guanidine gave the compound 2-(5-(2- (benzol[dJisoxazol-3-yl)vinyl)-l,2-dihydro-2-iminopyrimidin-4- yl) phenols 5. Moleculer descriptor properties were analyzed by using simple moleculer descriptor used by “Lipinski’s rule of 5”. The structures of compounds were established on the basis of spectral data. Synthesized compounds were screened for their antimicrobial activities.
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Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics