Awesome Chemistry Experiments For 1,2-Benzisoxazole-3-acetic Acid

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METHOD FOR SULFONATION OF 1,2-BENZISOXAZOLE-3-ACETIC ACID

An efficient method for the preparation of 1,2-benzisoxazole-3-methanesulfonic acid involves a reaction of 1,2-benzisoxazole-3-acetic acid in toluene with chlorosulfonic acid optionally mixed with an inert solvent in the presence of a particular Lewis base (ester or a nitrile).

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Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics