Chemical Research Letters, May 2021. In an article, author is Naidu, Kalaga Mahalakshmi, once mentioned the application of 629-25-4, Name is Sodium Laurate, molecular formula is C12H23NaO2, molecular weight is 222.2996, MDL number is MFCD00041754, category is benzisoxazole. Now introduce a scientific discovery about this category, SDS of cas: 629-25-4.
A series of thirty-six novel 5-(2-(4-(benzo[d]isoxazol-3-yl)piperazin-1-yl)acetyl)indolin-2one and 5-(2-(4-substitutedpiperazin-1-yl)acetyl)indolin-2-one analogues were synthesized, characterized and screened for their in vitro anti-tubercular activity against Mycobacterium tuberculosis H37Rv strain. These compounds exhibited minimum inhibitory concentration between 1.56 and 50 mu g/mL. Among these derivatives, compounds 10c, 10d, 10j, 10o and 10v (MIC 6.25 mu g/mL) displayed moderate activity, while compounds 10e, 10l, 10q, 10w,10x, 12d, 12e and 12i (MIC 3.12 mu g/mL) showed good anti-tubercular activity and compounds 10f, 10k, 10p, 10r, 12f, 12j and 12k (MIC 1.56 mu g/mL) exhibited excellent anti-tubercular activity. In addition, MTT assay was accomplished on the active analogues of the series against mouse macrophage (RAW 264.7) cells to evaluate the cytotoxic effect of the newly synthesized compounds and selectivity index of the compounds was determined. (C) 2015 The Authors. Published by Elsevier B.V. on behalf of King Saud University.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 629-25-4. The above is the message from the blog manager. SDS of cas: 629-25-4.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics