Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 3326-71-4, is researched, SMILESS is O=C(C1=CC=CO1)NN, Molecular C5H6N2O2Journal, Polyhedron called Investigation of DNA interaction and antiproliferative activity of mixed ligand dioxidomolybdenum(VI) complexes incorporating ONO donor aroylhydrazone ligands, Author is Dinda, Rupam; Panda, Arpita; Banerjee, Atanu; Mohanty, Monalisa; Pasayat, Sagarika; Tiekink, Edward R. T., the main research direction is molybdenum oxo Schiff arylhydrazone hydroxybenzaldehyde complex preparation redox potential; antitumor DNA binding molybdenum oxo Schiff arylhydrazone hydroxybenzaldehyde complex; crystal structure molybdenum oxo Schiff arylhydrazone hydroxybenzaldehyde complex.COA of Formula: C5H6N2O2.
Four new mixed ligand dioxidomolybdenum(VI) [MoVIO2L1-3(Q)] (1-3), [MoVIO2L4(Q)]2 (H2O) (4) [where Q = MeOH for 1 and imidazole for 2-4] complexes were synthesized using four different ONO donor aroylhydrazone ligands (H2L1-4). All the derived ligands and complexes were characterized by different physicochem. techniques, i.e., elemental anal., spectroscopic methods (UV-Vis, NMR and IR), and cyclic voltammetry. The mol. geometries of 1-4 were established by X-ray crystallog. which reveals the Schiff base ligands coordinate – the distorted octahedral metal centers in a di-neg. tridentate fashion. The complexes indicated moderate binding affinity (103 to 104 M-1) towards CT-DNA. Further, in vitro cytotoxicity activity of all the complexes were determined against HT-29 (colon cancer) and HeLa (cervical cancer) cell lines. Complex 4, due to the presence of a heterocyclic 2-hydroxy-1-naphthyl moiety in the ligand backbone, was found to be more biol. active in comparison to the others in the series.
This literature about this compound(3326-71-4)COA of Formula: C5H6N2O2has given us a lot of inspiration, and I hope that the research on this compound(2-Furoic hydrazide) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics