Chemistry is an experimental science, Product Details of 5117-19-1, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 5117-19-1, Name is 3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol, molecular formula is C16H34O9, belongs to benzisoxazole compound. In a document, author is Berton, Mateo.
Reactivity of Lithium beta-Ketocarboxylates: The Role of Lithium Salts
Lithium beta-ketocarboxylates 1(COOLi), prepared by the reaction of lithium enolates 2(Li+) with carbon dioxide, readily undergo decarboxylative disproportionation in THF solution unless in the presence of lithium salts, in which case they are indefinitely stable at room temperature in inert atmosphere. The availability of stable THF solutions of lithium beta-ketocarboxylates 1(COOLi) in the absence of carbon dioxide allowed reactions to take place with nitrogen bases and alkyl halides 3 to give alpha-alkyl ketones 1(R) after acidic hydrolysis. The sequence thus represents the use of carbon dioxide as a removable directing group for the selective monoalkylation of lithium enolates 2(Li+). The roles of lithium salts in preventing the disproportionation of lithium beta-ketocarboxylates 1(COOLi) and in determining the course of the reaction with bases and alkyl halides 3 are discussed.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 5117-19-1, in my other articles. Product Details of 5117-19-1.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics