Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 929-59-9, Name is 1,2-Bis(2-aminoethoxy)ethane, molecular formula is , belongs to Benzisoxazole compound. In a document, author is SATO, H, Computed Properties of C6H16N2O2.
STUDIES ON URICOSURIC DIURETICS .2. SUBSTITUTED 7,8-DIHYDROFURO[2,3-G]-1,2-BENZISOXAZOLE-7-CARBOXYLIC ACIDS AND 7,8-DIHYDROFURO[2,3-G]BENZOXAZOLE-7-CARBOXYLIC ACIDS
A series of substituted 7,8-dihydrofuro[2,3-g]-1,2-benzisoxazole-7-carboxylic acids 9 and 7,8-dihydrofuro[2,3-g]benzoxazole-7-carboxylic acids 12 were synthesized and evaluated for uricosuric and diuretic activities in rats. Many of the benzisoxazole derivatives 9 showed uricosuric and only weak diuretic activities, whereas the benzoxazoles 12 exhibited potent diuretic activities with little affecting urate excretion. Among these compounds, 5-chloro-7,8-dihydro-3-phenylfuro[2,3-g]-1,2-benzisoxazole-7-carboxylic acid (9b, AA-193) was found to be a potent uricosuric agent without diuretic activity and was selected for further development.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 929-59-9, in my other articles. Computed Properties of C6H16N2O2.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics