Category: 16263-53-9

Reference of 16263-53-9, Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 16263-53-9, Name is 3,5-Dichlorobenzo[d]isoxazole. In a document type is Patent,introducing its new discovery.

QUINUCLIDINYLOXY-ISOXAZOLE COMPOUNDS AND THEIR THERAPEUTIC USES

Compounds of formula (I): STR1 wherein R 1 is hydrogen, halogen or alkyl; R 2 is hydrogen, alkyl, optionally substituted phenyl or a heterocycle; or R 1 and R 2 together form a group of formula–CR 4 =CR 5–CR 6 =CR 7–, where R. sup. 4, R 5, R 6 and R 7 are hydrogen, halogen, alkyl group, alkoxy, halomethyl, alkylamino, dialkylamino, hydroxy, nitro, aliphatic carboxylic acylamino or amino; and R 3 is piperidyl, substituted piperidyl or quinuclidinyl. The compounds are useful in the treatment and prophylaxis of cognitive disorders, notably senile dementia, including Alzheimer’s disease. Processes for preparing the compounds are also provided.

Interested yet? Keep reading other articles of Safety of Benzo[b]furan-2-carboxaldehyde!, Reference of 16263-53-9

Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Electric Literature of 16263-53-9, Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 16263-53-9, Name is 3,5-Dichlorobenzo[d]isoxazole. In a document type is Patent,introducing its new discovery.

3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES

The present invention relates to 3,8-diaza-bicyclo[4.2.0]oct-8-yl amide derivatives of formula (I) Formula (I) wherein the relative configuration of the diazabicyclooctane moiety is cis; and wherein Ar1, and Ar 2 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as orexin receptor antagonists.

Electric Literature of 16263-53-9, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about Electric Literature of 16263-53-9

Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Chemistry, like all the natural sciences, Quality Control of 3,5-Dichlorobenzo[d]isoxazole, begins with the direct observation of nature¡ª in this case, of matter. In a Patent£¬Which mentioned a new discovery about 16263-53-9.

Isoxazole derivatives

An isoxazole compound having the following formula: wherein R1 represents hydrogen, halogen, alkyl, alkoxy, hydroxyl, alkylthio, amino, alkanoyl, alkanoylamino, alkanoyloxy, alkoxycarbonyl, carboxy, (alkylthio)thiocarbonyl, carbamoyl, nitro or cyano; R2 represents an amino; m is 1; n is 1 to 6; ring A represents a phenyl ring or a naphthyl ring; and X represents oxygen or sulfur. The isoxazole compound has an excellent monoamine oxidase inhibitory activity, and is useful for treating Parkinson’s disease, depression and Alzheimer’s disease.

Interested yet? Keep reading other articles of Related Products of 18959-30-3!, Quality Control of 3,5-Dichlorobenzo[d]isoxazole

Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Electric Literature of 16263-53-9, Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 16263-53-9, Name is 3,5-Dichlorobenzo[d]isoxazole. In a document type is Patent,introducing its new discovery.

1,2-benzoisoxazole derivative or its salt and brain-protecting agent comprising the same

This invention relates to a 1,2-benzoisoxazole derivative represented by the following general formula (I) or its salt: STR1

Electric Literature of 16263-53-9, Interested yet? Read on for other articles about Electric Literature of 16263-53-9!

Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

16263-53-9, Name is 3,5-Dichlorobenzo[d]isoxazole, belongs to Benzisoxazole compound, is a common compound. Formula: C7H3Cl2NOIn an article, once mentioned the new research about 16263-53-9.

Synthesis and Biological Evaluation of 1-(1,2-Benzisothiazol-3-yl)- and (1,2-Benzisoxazol-3-yl)piperazine Derivatives as Potential Antipsychotic Agents

Members of the series of title compounds were tested for potential antipsychotic activity in relevant receptor binding assays and behavioral screens.Structure-activity relationships within the series are discussed.Compound 24 (BMY 13859-1), a (1,2-benzisothiazol-3-yl)piperazine derivative, was selected for further study because of its potent and selective profile in primary CNS tests.It was active in the Sidman avoidance paradigm and blocked amphetamine-induced stereotyped behavior in dogs for up to 7 h.The compound’s lack of typical neuroleptic-like effects in therat catalepsy test and its failure to produce dopamine receptor supersensitivity following chronic administration indicate that it should not cause the movement disorders commonly associated with antipsychotic therapy.Although 24 has potent affinity for dopaminergic binding sites, its even greater affinity for serotonin receptors suggests that a serotonergic component may be relevant to its atypical profile.Compound 24 is currently undergoing clinical evaluation in schizophrenic patients.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Formula: C7H3Cl2NO, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about Formula: C7H3Cl2NO

Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 16263-53-9, Name is 3,5-Dichlorobenzo[d]isoxazole,introducing its new discovery., Computed Properties of C7H3Cl2NO

Isoxazole derivatives

An isoxazole compound having the following formula: wherein R1 represents hydrogen, halogen, alkyl, alkoxy, hydroxyl, alkylthio, amino, alkanoyl, alkanoylamino, alkanoyloxy, alkoxycarbonyl, carboxy, (alkylthio)thiocarbonyl, carbamoyl, nitro or cyano; R2 represents an amino; m is 1; n is 1 to 6; ring A represents a phenyl ring or a naphthyl ring; and X represents oxygen or sulfur. The isoxazole compound has an excellent monoamine oxidase inhibitory activity, and is useful for treating Parkinson’s disease, depression and Alzheimer’s disease.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 16263-53-9, and how the biochemistry of the body works.Computed Properties of C7H3Cl2NO

Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Electric Literature of 16263-53-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.16263-53-9, Name is 3,5-Dichlorobenzo[d]isoxazole, molecular formula is C7H3Cl2NO. In a Patent£¬once mentioned of 16263-53-9

QUINUCLIDINYLOXY-ISOXAZOLE COMPOUNDS AND THEIR THERAPEUTIC USES

Compounds of formula (I): STR1 wherein R 1 is hydrogen, halogen or alkyl; R 2 is hydrogen, alkyl, optionally substituted phenyl or a heterocycle; or R 1 and R 2 together form a group of formula–CR 4 =CR 5–CR 6 =CR 7–, where R. sup. 4, R 5, R 6 and R 7 are hydrogen, halogen, alkyl group, alkoxy, halomethyl, alkylamino, dialkylamino, hydroxy, nitro, aliphatic carboxylic acylamino or amino; and R 3 is piperidyl, substituted piperidyl or quinuclidinyl. The compounds are useful in the treatment and prophylaxis of cognitive disorders, notably senile dementia, including Alzheimer’s disease. Processes for preparing the compounds are also provided.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 16263-53-9, and how the biochemistry of the body works.Electric Literature of 16263-53-9

Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In a patent, 16263-53-9, molecular formula is C7H3Cl2NO, introducing its new discovery. Recommanded Product: 16263-53-9

Synthesis and Biological Evaluation of 1-(1,2-Benzisothiazol-3-yl)- and (1,2-Benzisoxazol-3-yl)piperazine Derivatives as Potential Antipsychotic Agents

Members of the series of title compounds were tested for potential antipsychotic activity in relevant receptor binding assays and behavioral screens.Structure-activity relationships within the series are discussed.Compound 24 (BMY 13859-1), a (1,2-benzisothiazol-3-yl)piperazine derivative, was selected for further study because of its potent and selective profile in primary CNS tests.It was active in the Sidman avoidance paradigm and blocked amphetamine-induced stereotyped behavior in dogs for up to 7 h.The compound’s lack of typical neuroleptic-like effects in therat catalepsy test and its failure to produce dopamine receptor supersensitivity following chronic administration indicate that it should not cause the movement disorders commonly associated with antipsychotic therapy.Although 24 has potent affinity for dopaminergic binding sites, its even greater affinity for serotonin receptors suggests that a serotonergic component may be relevant to its atypical profile.Compound 24 is currently undergoing clinical evaluation in schizophrenic patients.

If you are interested in 16263-53-9, you can contact me at any time and look forward to more communication. Recommanded Product: 16263-53-9

Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Application of 16263-53-9, In heterogeneous catalysis, the catalyst is in a different phase from the reactants. At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way.16263-53-9, Name is 3,5-Dichlorobenzo[d]isoxazole, molecular formula is C7H3Cl2NO. In a Patent£¬once mentioned of 16263-53-9

1,2-benzoisoxazole derivative or its salt and brain-protecting agent comprising the same

This invention relates to a 1,2-benzoisoxazole derivative represented by the following general formula (I) or its salt: STR1

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 16263-53-9 is helpful to your research. Application of 16263-53-9

Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Synthetic Route of 16263-53-9, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 16263-53-9, Name is 3,5-Dichlorobenzo[d]isoxazole, molecular formula is C7H3Cl2NO, introducing its new discovery.

3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES

The present invention relates to 3,8-diaza-bicyclo[4.2.0]oct-8-yl amide derivatives of formula (I) Formula (I) wherein the relative configuration of the diazabicyclooctane moiety is cis; and wherein Ar1, and Ar 2 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as orexin receptor antagonists.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 16263-53-9

Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics