Category: 610-09-3

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about Coordination preference of 1,2-bis((1H-imidazole-1-yl)methyl)benzene and different carboxylate ligands with transition metal ions directed by weak interactions, the main research direction is copper cadmium silver imidazoleylmethylbenzene hydroxybenzoate cyclohexenecarboxylate cyclohexanecarboxylate polymer preparation; thermal stability luminescence transition metal imidazoleylmethylbenzene hydroxybenzoate cyclohexenecarboxylate cyclohexanecarboxylate; crystal structure transition metal imidazoleylmethylbenzene hydroxybenzoate cyclohexenecarboxylate cyclohexanecarboxylate.Formula: C8H12O4.

Three novel metal-organic complexes, formulated as [Cu2(2-HBA)2(bimb)4] (1), {[Cd(CEDA)(bimb)]·H2O}n (2), and {[Ag2(bimb)2]·(1,4-CDA)·13H2O} (3) (bimb = 1,2-bis((1H-imidazole-1-yl)methyl)benzene; 2-HBA = 2-hydroxybenzoic acid; CEDA = cyclohex-4-ene-1,2-dicarboxylic acid; 1,4-CDA = cyclohexane-1,4-dicarboxylic acid), were synthesized by self-assembly of mixed ligands with Cu(II), Cd(II), and Ag(I) under hydrothermal conditions and characterized by means of single-crystal X-ray diffraction, X-ray powder diffraction, IR spectra, thermogravimetric anal., fluorescence spectra and UV-vis absorption spectra. 1 Is shown as a 0D structure, which is formed by Cu2+, 2-HBA ligands and bimb ligands. 2 Displays a 1D ladder structure, which is built by Cd2+, CEDA ligands and bimb ligands, and it is assembled into 2D structure by hydrogen bonding. 3 Possesses a 0D [Ag(bimb)]2 dimer which is assembled into 3D structure by the Ag-O weak interaction and hydrogen bonding. Interestingly, a rare 13-core water cluster participates in forming the network of 3. The UV-vis spectrum and luminescence properties were also studied and discussed.

After consulting a lot of data, we found that this compound(610-09-3)Formula: C8H12O4 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about Evaluation of the anticorrosivity by low-energy photoelectron emission of the magnetic metal particles for magnetic recording media.Application In Synthesis of cis-Cyclohexane-1,2-dicarboxylic acid.

The correlation between the anticorrosivity and the intensity of the low-energy photoelectron emission of Fe particles for magnetic recording was studied. Particles with higher anticorrosivity showed lower emission intensity. Particles treated with cis-1,2-cyclohexyldicarboxylic acid showed a higher emission threshold. This higher threshold was explained by the formation of a surface potential barrier on the outer layer of γ-Fe2O3 by anionic species.

The article 《Evaluation of the anticorrosivity by low-energy photoelectron emission of the magnetic metal particles for magnetic recording media》 also mentions many details about this compound(610-09-3)Application In Synthesis of cis-Cyclohexane-1,2-dicarboxylic acid, you can pay attention to it, because details determine success or failure

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《The configuration of polymethylenedicarboxylic acids. I. The dissociation constants of the cyclohexanedicarboxylic acids》. Authors are Kuhn, Richard; Wassermann, Albert.The article about the compound:cis-Cyclohexane-1,2-dicarboxylic acidcas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O).Category: benzisoxazole. Through the article, more information about this compound (cas:610-09-3) is conveyed.

The 1st and 2nd dissociation constants for the cyclohexanedicarboxylic acids in water and in 50% MeOH are given as follows (-log K, -log K2 and K1/K2, resp.): In H2O: o-cis, 4.34 (19°), 6.76 (19°), 267; o-trans, 4.18 (18°), 5.93 (19°), 56; m-cis, 4.10 (16°), 5.46 (16°), 23; m-trans, 4.31 (19°), 5.73 (19°), 26; p-cis, 4.44 (20°), 5.79 (19°), 22; p-trans, 4.18 (16°), 5.42 (19°), 17. In 50% MeOH: o-cis, 5.26 (18°), 8.20 (18°), 885; o-trans, 5.38 (18°), 7.31 (18°), 85; m-cis, 5.25 (17°), 6.83 (17°), 38; m-trans, 5.48 (19°), 7.40 (19°), 83; p-cis, 5.59 (19°), 7.15 (19°), 36; p-trans, 5.32 (18°), 6.81 18°), 30. The configurations of the various isomeric forms of the hexahydrophthalic acids are graphically presented.

The article 《The configuration of polymethylenedicarboxylic acids. I. The dissociation constants of the cyclohexanedicarboxylic acids》 also mentions many details about this compound(610-09-3)Category: benzisoxazole, you can pay attention to it, because details determine success or failure

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Stereoisomeric biologically active compounds. I. Some conversions of cis-4-chloro-4-cyclohexene-1,2-dicarboxylic acid》. Authors are Rashidyan, L. G.; Tatevosyan, G. T..The article about the compound:cis-Cyclohexane-1,2-dicarboxylic acidcas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O).Recommanded Product: 610-09-3. Through the article, more information about this compound (cas:610-09-3) is conveyed.

cf. Baeyer, Ann. Chem. 258, 215(1890); U.S. 1,967,862, CA 28, 5994. To 10 g. cis-4-chloro-4-cyclohexene-1,2-dicarboxylic acid (I) and 60 ml. H2O, under cooling and stirring, a solution of 21 g. KMnO4 in 650 650 ml. H2O was added over 3 hrs. The cooling and stirring was another 2 hrs. and the mixture left standing overnight, yielding meso-butane-1,2,3,4-tetracarboxylic acid m. 191-2°. I (204.5 g.) and 15 ml. concentrated H2SO4 in 500 ml. absolute MeOH was refluxed for 8 hrs. Dimethyl cis-4-chloro-4-cyclohexene-1,2-dicarboxylate (II), b5 148-50°, d204 1.0553, n20D 1.4935 was obtained in 71.3% yield. II (20 g.) and 18 ml. 85% H2NNH2 was refluxed for 3 hrs. Trans-4-chloro-4-cyclohexene-1,2-dicarboxylic acid dihydrazide (III) m. 222-4° (60% EtOH) was obtained in 69.5% yield. To 30 g. III in 105 ml. 10% HCl and 280 ml. CH2Cl2 at 18-20°, a solution of 20.8 g. NaNO3 in 48.5 ml. H2O was slowly added. The nonaqueous layer was dried, filtered, and treated with 160 ml. absolute EtOH. The CH2Cl2 was evaporated, the mixture refluxed for 2 hrs., 210 ml. 40% NaOH added and steam distilled The distillate was acidified with 10% HCl giving the trans-4-chloro-1,2-diamino-4-cyclohexene-2HCl m. 326-8° in 72.1% yield. III (38 g.) and a solution of 26.6 g. NaOH in 350 ml. H2O was refluxed for 12 hrs. and acidified, giving trans-4-chloro-4-cyclohexene-1,2-dicarboxylic acid (IV) m. 115-17° (H2O) in 89.8% yield. IV (10 g.) was oxidized with KMnO4 as described above, giving the dianhydride of dl-butane-1,2,3,4-tetracarboxylic acid m. 172-3°. A solution of 21 g. IV, 8 g. NaOH and 70 ml. H2O was hydrogenated in an autoclave in the presence of 35 g. Ni on Cr2O3 at 100° and 100 atm. The solution was filtered and acidified giving trans-cyclohexane-1,2-dicarboxylic acid (V) m. 220° (Me2O) in 78.2% yield. I (60 g.) and 23.5 g. NaOH in 200 ml. H2O was hydrogenated as described above giving cis-cyclohexane-1,2-dicarboxylic acid (VI), m. 192°, in 92.1% yield. A mixture of 8 g. VI and 20 ml. concentrated HCl was heated in a sealed tube at 180° for 8-10 hrs. and V, m. 220-1°, was obtained in 88.8% yield.

The article 《Stereoisomeric biologically active compounds. I. Some conversions of cis-4-chloro-4-cyclohexene-1,2-dicarboxylic acid》 also mentions many details about this compound(610-09-3)Recommanded Product: 610-09-3, you can pay attention to it, because details determine success or failure

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about Potassium selectivities of bis(benzo-15-crown-5) derivatives obtained from cyclohexanedicarboxylic acids, the main research direction is crown ether neutral carrier selective electrode; ion selective electrode crown ether carrier; potassium selective electrode crown ether carrier; cyclohexane derivative crown ether electrode; benzene derivative crown ether electrode.Category: benzisoxazole.

Several bis(benzo-15-crown-5) derivatives containing a cyclohexane or benzene ring in the bridge chain were synthesized as neutral carriers of coated-wire K+-selective electrodes. The bis(benzocrown ether) derivative obtained from cis-1,2-cyclohexanedicarboxylic acid was outstandingly K-selective.

The article 《Potassium selectivities of bis(benzo-15-crown-5) derivatives obtained from cyclohexanedicarboxylic acids》 also mentions many details about this compound(610-09-3)Category: benzisoxazole, you can pay attention to it, because details determine success or failure

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Application of 610-09-3. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about Hydrolysis and interactions of D-cellobiose with polycarboxylic acids. Author is Amarasekara, Ananda S.; Wiredu, Bernard; Lawrence, Yen Maroney.

The hydrolysis of cellulose model compound D-cellobiose was studied with a series of eight common polycarboxylic acids and two monocarboxylic acids in aqueous medium using 0.500 mmol -COOH/L at 170 °C. The maleic acid showed the highest catalytic activity with turnover frequency (TOF) of 29.5 h-1. The interaction of carboxylic acids with D-cellobiose in DMSO-d6 was studied by determination of the pseudo first-order rate constant kH of anomeric -OH exchange rate in cellobiose using 1H NMR spectroscopy. The maleic, oxalic and citric acids showed infinitely large kH values indicating very strong interactions with D-cellobiose. The next highest interactions were found with phthalic acid (kH = 248.8 Hz). The FT-IR studies showed significant carboxylic acid C=O stretching frequency shifts (ΔνC=O) of 12, 13 and 10 cm-1 for maleic, oxalic and acetic acids resp. in mixtures with D-cellobiose.

After consulting a lot of data, we found that this compound(610-09-3)Application of 610-09-3 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Wang, Ling; Wan, Chao; Wang, Hongqin; Chen, Hongtao; Zhu, XiaoMeng; Li, Mingyu published an article about the compound: cis-Cyclohexane-1,2-dicarboxylic acid( cas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O ).Name: cis-Cyclohexane-1,2-dicarboxylic acid. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:610-09-3) through the article.

To improve the elec. conductivity of the dicyandiamide-cured elec. conductive adhesives (ECAs), short-chain difunctional acids with various structures including oxalic acid, succinic acid, adipic acid, phthalic acid and cis-hexahydrophthalic acid were introduced in-situ to replace the commonly used surfactant-stearic acid on the silver filler surface. Oxalic acid, phthalic acid and cis-hexahydrophthalic acid deteriorated the elec. conductivity of ECAs whereas the elec. conductivity was improved significantly with the addition of succinic acid and adipic acid. Moreover, the storage performance, viscosity, curing behavior, bulk resistivity and the shear strength of ECAs with varied content of adipic acid had been further studied. With the increment of adipic acid, the curing temperature of ECAs decreased, while the reaction between dicyandiamide and adipic acid happened as the content reached 0.3 wt%. And the adipic acid not just improved the elec. conductive, but also improved the shear strength without adversely affected the storage performance of ECAs. As the content of adipic acid reached 0.3 wt%, the lowest bulk resistivity 3.8×10-4 Ω cm was obtained, at the content of 0.5 wt%, the shear strength was improved to 18.5 MPa.

After consulting a lot of data, we found that this compound(610-09-3)Name: cis-Cyclohexane-1,2-dicarboxylic acid can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Morawetz, Herbert; Choi, Ling Siu published an article about the compound: cis-Cyclohexane-1,2-dicarboxylic acid( cas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O ).Quality Control of cis-Cyclohexane-1,2-dicarboxylic acid. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:610-09-3) through the article.

Succinic acid and substituted succinic acids undergo conformational transitions during ionization, and these are expected to affect their ionization equilibrium The 1H NMR data on the dependence of the conformational equilibrium of succinic acid and meso-2,3-dimethylsuccinic acid on their degree of ionization are interpreted in terms of the ratio of the 2nd ionization constants of the gauche and trans isomer, K2g/K2t, and the equilibrium constant Kc for the gauche-trans transition of the unionized acid. The K2g/K2t ratios obtained for the 2 above acids are compared with theratio of the 2nd ionization constants of cis- and trans-cyclohexane-1,2-dicarboxylic acids used as model compounds in which the carboxyls are gauche and trans to each other.

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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《The heats of hydration and energy contents of cis- and trans-cyclohexane-1,2-dicarboxylic acids, and their primary ions》. Authors are Wassermann, Albert.The article about the compound:cis-Cyclohexane-1,2-dicarboxylic acidcas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O).Reference of cis-Cyclohexane-1,2-dicarboxylic acid. Through the article, more information about this compound (cas:610-09-3) is conveyed.

The following values were obtained for the cis- and trans-cyclohexane-1,2-dicarboxylic acids and their ions, resp.: heat of combustion, kg.-cal./mole (constant temperature) 931.9, 929.5; heat of solution + first heat of ionization, -7.49, -6.48; energy content of primary anion in dilute solution, kg.-cal./mole 939.4, 936.0; mol. volume at 0° 126.5, 120.4; second heat of ionization +0.30, +0.24. The first ionization constant of the cis acid increases with rise in temperature, while that of the trans decreases. This leads to the conclusion that the trans ion is more hydrated than the cis ion, although the heat of hydration of the undissociated cis is not measurably greater than that of the trans acid.

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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Name: cis-Cyclohexane-1,2-dicarboxylic acid. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about Organic ligand binding by a hydrophobic cavity in a designed tetrameric coiled-coil protein. Author is Mizuno, Toshihisa; Hasegawa, Chinatsu; Tanabe, Yoichi; Hamajima, Kenta; Muto, Takashi; Nishi, Yoshinori; Oda, Masayuki; Kobayashi, Yuji; Tanaka, Toshiki.

The design and characterization of a hydrophobic cavity in de novo designed proteins provides a wide range of information about the functions of de novo proteins. We designed a de novo tetrameric coiled-coil protein with a hydrophobic pocketlike cavity. Tetrameric coiled coils with hydrophobic cavities have previously been reported. By replacing one Leu residue at the a position with Ala, hydrophobic cavities that did not flatten out due to loose peptide chains were reliably created. To perform a detailed examination of the ligand-binding characteristics of the cavities, we originally designed two other coiled-coil proteins: AM2, with eight Ala substitutions at the adjacent a and d positions at the center of a bundled structure, and AM2W, with one Trp and seven Ala substitutions at the same positions. To increase the association of the helical peptides, each helical peptide was connected with flexible linkers, which resulted in a single peptide chain. These proteins exhibited CD spectra corresponding to superhelical structures, despite weakened hydrophobic packing. AM2W exhibited binding affinity for size-complementary organic compounds The dissociation constants, Kd, of AM2W were 220 nM for adamantane, 81 μM for 1-adamantanol, and 294 μM for 1-adamantane acetic acid, as measured by fluorescence titration analyses. Although it was contrary to expectations, AM2 did not exhibit any binding affinity, probably due to structural defects around the designed hydrophobic cavity. Interestingly, AM2W exhibited incremental structure stability through ligand binding. Plugging of structural defects with organic ligands would be expected to facilitate protein folding.

After consulting a lot of data, we found that this compound(610-09-3)Name: cis-Cyclohexane-1,2-dicarboxylic acid can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics