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Dental releasing materials

Combining nanosized particles of a source of desired dental restorative, repair or therapeutic materials with strengthening agents in various generally nanosized form such as whiskers, fibers, particles and the like in a resin matrix provides a highly strain resistant composite which more effectively releases the therapeutic agents. The utilization of nano sized particles of the therapeutic agent in the combination enables observation of significantly improved therapeutic results.

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Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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Adhesion promoter composition for polyolefinic membranes

Composition, comprising?at least one organic polymer,?at least one monomer from the group of acrylates,?at least one catalyst from the group of tertiary organic amines,?at least one solvent.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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Different peripheral substituted phthalocyanines: Synthesis, characterization, aggregation behavior, antioxidant and antibacterial activity

In this study, a novel phthalonitrile, 4-chloro-5-(2-((2-hydroxyethyl)(p-tolyl)amino)ethoxy)phthalonitrile (3), and its metallophthalocyanine derivatives (4-6) are prepared by cyclotetramerization with appropriate metal salts in dimethylformamide. The newly prepared compounds have been characterized by several spectroscopic techniques. All compounds are evaluated for their antioxidant and antibacterial potential. For the antioxidant studies, three tests are applied; DPPH (2,2-diphenyl-1-picrylhydrazylradical) scavenging, metal chelating and reducing power activity. Compound 4 exhibits the best DPPH scavenging activity as 35.2% at 100 mg/L concentration. The metal chelating activities of compounds 3 and 4 are 69.7% and 56.4%, respectively. Reducing power activities of compounds 3 and 4 are higher than alpha-tocopherol which is used as positive control. All compounds show moderate antibacterial activity when compared to the standard antibiotics, amikacin and tetracycline.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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Chlorinated poly(propylene carbonate) and preparation method thereof

This invention provides a chlorinated poly(propylene carbonate) and the preparation method thereof, the chlorinated poly(propylene carbonate) is as represented by formula (I). Compared to the prior poly(propylene carbonate)s, the chlorinated poly(propylene carbonate) has relatively stronger electronegativity due to the presence of chlorine atoms and the interaction of the chlorinated poly(propylene carbonate) with other polar materials can be enhanced, so that it can be widely used as a compatilizer, a binder, a paint, an ink, and the like. After the introduction of chlorine atoms, hydrogen bond interaction is generated within the chlorinated poly(propylene carbonate), so that its processability and mechanical properties are both improved. Furthermore, the chlorine atom may improve the flame retardancy of chlorinated poly(propylene carbonate) materials.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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Dental adhesive composition

A dental adhesive composition which can quickly be hardened even in the presence of oxygen without using a radical generating agent such as a peroxide or a photopolymerization initiator, to give high bond strength, the composition including, in specific amounts, (A) a carboxylic acid compound having a (meth)-acryloyl group and a carboxyl group, both of which are attached to an aromatic ring; (B) a bisphenol A derivative having two (meth) acryloyl groups; (C) a hydroxylalkyl (meth)acrylate; (D) a (meth)acrylate derivative having an acid group; and (E) at least one polymerization initiator selected from the group consisting of aromatic amines, aliphatic amines, and aromatic sulfinic acids; the composition being substantially free from any radical polymerization initiator.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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Primer composition

The present invention provides a primer composition comprising (i) 0.5-90% by weight of water, (ii) 5-90% by weight of a polymerizable compound having hydroxyl group, (iii) 0.1-90% by weight of a polymerizable compound having acidic group, and (iv) 0.01-30% by weight of a curing agent. When dental adhesive restorative materials such as dental resin cements, composite resins, PMMA resins and the like are made to adhere directly or through bonding agents to substrates such as vital hard tissues, especially an enamel or a dentin of natural teeth, glass ionomer cements and the like, the primer composition is able to impart a strong and durable adhesive property between the both without treating said substrates with an acid and the like.

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Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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Curable acrylate polymer compositions featuring improved flexural characteristics

The invention describes acrylic and methacrylic acid ester-based polymeric materials containing as flexibilizing and brittleness reducing agents 1-60% of C4-C8 polyalkylene or polyalkyldiene compounds, preferably having a molecular weight of 300-2100, and the use of such materials in dentistry and medicine.

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Benzisoxazole – Wikipedia,
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PHOTOCURABLE RESIN COMPOSITION

An object of the present invention is to provide a photocurable resin composition having excellent thick-film curability and further excellent storage stability, and a cured product of the photocurable resin composition has a high concealing effect.The present invention is a photocurable resin composition containing components (A) to (E): a component (A): a leuco dye; a component (B): a photoacid generator; a component (C): a radical polymerizable compound (except for a (meth)acrylate having a tertiary amine skeleton); a component (D): a photoradical polymerization initiator; and a component (E): a tertiary amine compound.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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The Stereochemistry of 4,8-Dimethyl-6-phenyl-5,6,7,8-tetrahydro-4H-1,3,6-dioxazocin-2-ones Using NMR

Two isomeric 4,8-dimethyl-6-phenyl-5,6,7,8-tetrahydro-4H-1,3,6-dioxazocin-2-ones were prepared, and their pmr and cmr spectra were examined.From the tris(dipivaloylmethanato) europium (Eu(dpm)3) shift reagent and the dihedral angle, the title compounds are found to exist in the eq-ax and eq-eq methyl groups with boat-chair form.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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Hypoxia-Selective Antitumor Agents. 3. Relationships between Structure and Cytotoxicity against Cultured Tumor Cells for Substituted N,N-Bis(2-chloroethyl)anilines

A series of aniline mustards with a wide range of electron-donating and -withdrawing substituents in the 3- and 4-positions has been synthesized and evaluated for cytotoxicity in cell culture to examine the potential of using nitro group deactivated nitrogen mustards for the design of novel hypoxia-selective anticancer drugs (Denny, W.A.; Wilson, W.R.J.Med Chem. 1986, 29, 879).Hydrolytic half-lives in tissue culture media, determined by bioassay against a cell line (UV4) defective in the repair of DNA interstrand cross-links showed the expected dependence on the Hammett electronic parameter, ?, varying from 0.13 h for the 4-amino analogue to >100 h for analogues with strongly electron-withdrawing substituents.Cytotoxic potencies in aerobic UV4 cultures showed a similar dependence on ?.This dependence predicted that the 4-nitroaniline mustard would be 7200-fold less potent than its potential six-electron reduction product, the 4-amino compound, in growth inhibition assays using a 1-h drug exposure.The measured differential was much lower (225-fold) because of the instability of the latter compound, but a differential of 17500-fold was observed in the initial rate of killing by using a clonogenic assay.The potential for formation of reactive mustards by reduction to the amine or hydroxylamine was demonstrated by the 4-nitroso compound, which had an aerobic toxicity similar to that of the amine.Although these features confirmed the original rationale, the 3-nitro- and 4-nitroaniline mustards had only minimal hypoxic selectivity against UV cells.Toxicity to hypoxic cells appears to be limited by the low reduction potentials of these compounds and consequent lack of enzymatic nitroreduction.However, this study has demonstrated that nitro groups can be used to latentiate aromatic nitrogen mustards and indicates that examples with higher reduction potentials could provide useful hypoxia-selective therapeutic agents.

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Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics