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66033-92-9, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 66033-92-9, molcular formula is C8H7NO2, introducing its new discovery.

5-Thioxylopyranose Compounds

5-thioxylose compounds, especially 5-thioxylopyranose compounds, a process for their preparation, and their use for treating and/or inhibiting thromboses, especially venous thromboses. The compounds correspond to formula I: in which the pentapyranosyl group represents a free or substituted 5-thio-beta-D-xylopyranosyl group; R?, R? and R?? each independently represent a hydrogen atom, a C2-C6 acyl group, or two adjacent ones of them form a 1-methylethylidene bridge; X1 and X2 each represent carbon or nitrogen; Y1 and Y2 each independently represent carbon, nitrogen, sulfur or oxygen, with the proviso that if Y2 represents oxygen or sulfur, then Y1 represents carbon or nitrogen; R1, R2, R3, R4 and R5 each independently represent hydrogen, a COOR6 group where R6 represents hydrogen or a C1-C4 alkyl group optionally substituted by a phenyl ring, a halogen atom or a ?COOR6 group; a C1-C4 alkoxy group; a C1-C6 acyl group; a benzoyl group or a phenyl ring; and the addition salts and/or active metabolites of such compounds.

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Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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Triflic anhydride: A mild reagent for highly efficient synthesis of 1,2-benzisoxazoles, isoxazolo, and isothiazolo quinolines without additive or base

The synthetic utility of trifluoromethanesulphonic anhydride (triflic anhydride, TA) without additive or base for the high-yielding synthesis of a wide variety of 1,2-benzisoxazoles from 2-hydroxyaryl aldoximes and ketoximes under mild conditions has been carried out for the first time. As a continuation of our study, syntheses of isoxazolo and isothiazolo quinolones have also been demonstrated using triflic anhydride under similar conditions. This method is simple and has benefits from the easy way to isolate the products in excellent yields.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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Synthesis of New Isoxazoles from Isoxazolines, Chalkones, Chalkone Dibromides, Epoxides and Acetylated Ketoximes and Their Conversion into Novel Heterocycles

A convenient and easy conversion of 2-isoxazolines (II) to isoxazoles (V) via N-bromosuccinimide bromination and subsequent dehydrobromination with bases is described.The isoxazoles have also been synthesized from chalkones (I), chalkone dibromides (III) and chalkone epoxides (IV). 1,2-Benzisoxazoles (IX) and naphth<2,1-d>isoxazoles (XIV) have been prepared by the pyrolysis of acetylated ketoximes (VIII and XIII).Methylene-4,4′-bis(3-acylnaphthols) (XVIa-c), prepared by the action of paraformaldehyde on 2-acylnaphthols (XIa-c) in boiling amyl alcohol, are converted into dioximes (XVIIa-c) and then into bis(oxime-acetates) (XVIIIa-c) which on pyrolysis undergo cyclization to give methylene-5,5′-bis(3-alkylnaphth<2,1-d>isoxazoles).Methylene-5,5′-bis(3-methylnaphth<2,1-d>isoxazole (XIXa) on condensation with benzaldehyde and p-anisaldehyde gives the corresponding styryl drivatives (XXa,b).Compounds XIXa-c and XXa,b have also been prepared by the action of paraformaldehyde on 3-alkyl- and 3-styryl-naphth<2,1-d>isoxazoles (XIVa-c and XVa,b) in boiling xylene.The styryl derivatives Xa-d and XVa,b react smoothly with maleic anhydride to give 4-aryl-1,3-dioxo-1,3a,4,1Ob-tetrahydro-2,10-dioxa-10a-aza–3H-cyclopentafluorenes (XXIa-d) and 4-aryl-1,3-dioxo-1,3a,4,12b-tetrahydro-2,12-dioxa-12-aza-3H-cyclopentabenzofluorenes (XXIIIa,b).The fluorenes XXIa and XXIIIa on hydrolysis give 7-hydroxy-3-phenyl-2,3-dihydro-1H-pyrido<1,2-b><1,2>benzisoxazole-1,2-dicarboxylic acid (XXII) and 3-phenyl-2,3-dihydro-1H-pyrido<1,2-b>benzo<1,2>benzisoxazole-1,2-dicarboxylic acid (XXIV), respectively.

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Synthesis of novel benzothiozole and benzisoxazole functionalized unsymmetrical alkanes and of there antimicrobial activity

Novel unsymmetrical alkanes 4 and 5 have been independently synthesized in single pot from 2-amino 5/6hydroxybenzothiazole, 6-hydroxy-3-methyl-l,2- benzisoxazole and different dihaloalkanes [X-(CH2)n-X]. The compounds 4 and 5 have been screened for antimicrobial activity and some of them havefceen found to show promising activity.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

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A Benz wicked zuozuo apperception compound derivative and its application (by machine translation)

The present invention provides a Benz wicked zuozuo apperception compound derivative and its application, in vitro receptor binding test shows, the present invention provides the compounds of H3 Receptor has high affinity, can be used for improving the central nervous system disease, such as schizophrenia, cognitive disorders, pain, sleeping and the like; with the H1 Low receptor affinity, and then will not produce a side effect. (by machine translation)

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Benzisoxazole – Wikipedia,
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Synthesis of Furano<2,3-g>-1,2-benzisoxazoles

Several Furano<2,3-g>-1,2-benzisoxazoles have been synthesised by the condensation of 7-acyl-3-alkyl-6-hydroxybenz-(1,2)-isoxazoles with phenylacyl halides/ethyl bromoacetate.

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A novel method for the highly efficient synthesis of 1,2-benzisoxazoles under neutral conditions using the Ph3P/DDQ system

The use of Ph3P/DDQ offers a novel, neutral and highly efficient method for the efficient conversion of 2-hydroxyaryl aldoximes and ketoximes to 1,2-benzisoxazoles in excellent yields at room temperature.

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