Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Methyl tetrahydrofuran-2-carboxylate, is researched, Molecular C6H10O3, CAS is 37443-42-8, about Studies on flavor components in shoyu. Part VIII. Shoyu (soy sauce) flavor components: neutral fraction.Quality Control of Methyl tetrahydrofuran-2-carboxylate.
From the vacuum distilled volatiles of shoyu, a neutral fraction was obtained. Shoyu as also directly extracted with CH2Cl2 and then the extract was separated into 10 (A-J) fractions. The J fraction was a neutral one. The J fraction was further separated into 12 fractions by liquid column chromatog. All fractions obtained were analyzed by gas chromatog. and combined gas chromatog.-mass spectrometry. Consequently, 142 components were identified, 82 of which have not been reported previously as volatile constituents of shoyu. The identified compounds were 37 hydrocarbons, 22 alcs., 22 carbonyls, 22 esters, 12 furans, 6 sulfurous compounds, 1 pyrone, 5 phenols, 1 furanone, 1 acid, 1 lactone, and 12 other compounds From the results of quant. anal. and organoleptic evaluation, phenylacetaldehyde [122-78-1] is considered to be most important in the neutral fraction.
There is still a lot of research devoted to this compound(SMILES：O=C(C1OCCC1)OC)Quality Control of Methyl tetrahydrofuran-2-carboxylate, and with the development of science, more effects of this compound(37443-42-8) can be discovered.
Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics