In chemical reaction engineering, simulations are useful for investigating and optimizing a particular reaction process or system., Category: Benzisoxazole, Introducing a new discovery about 427-49-6, Name is alpha-Cyclopentylmandelic Acid, molecular formula is C13H16O3, belongs to benzisoxazole compound. In a document, author is Yamada, H.
To confirm the assumption that 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole (E3040) acts on urate reabsorption by inhibiting urate-anion exchange at the luminal membrane of renal tubules, we investigated the inhibitory effect of E3040 and its two conjugated metabolites on hydroxyl ion (OH-) gradient-dependent urate uptake into brush border membrane vesicles from rat renal cortex and compared it with other uricosuric agents. The order of potency was AA193 (5-chloro-7,8-dihydro-3-phenylfuro[2,3-g]-1,2-benzisoxazole-7-carboxylic acid)> benzbromarone > E3040 > probenecid > E3040 sulfate > E3040 glucuronide. Furthermore, kinetic analysis revealed that E3040 may be a competitive inhibitor of the OH- gradient-dependent uptake of urate into brush border membrane vesicles. (C) 2000 Elsevier Science B.V. All rights reserved.
I am very proud of our efforts over the past few months and hope to 427-49-6 help many people in the next few years. Category: Benzisoxazole.
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Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics