Yang, Min; Chen, Jing; He, Chen; Hu, Xin; Ding, Yechun; Kuang, Ying; Liu, Jinbiao; Huang, Qitong published an article about the compound: Methyl 2,4-dichloronicotinate( cas:442903-28-8,SMILESS:ClC1=C(C(=O)OC)C(=CC=N1)Cl ).Application of 442903-28-8. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:442903-28-8) through the article.
An alternative process of Pd-catalyzed C-4 selective coupling of 2,4-dichloropyridines with boronic esters was developed, which afforded 24 examples of C-4 coupled pyridines in moderate to good yields. After further arylation, 21 examples of C-2, C-4 diarylated pyridines with a significant photophys. property were obtained, which were applied as pyridine-based dyes into live-cell imaging with good biocompatibility and low toxicity.
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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics