Downstream synthetic route of 36216-80-5

As the paragraph descriping shows that 36216-80-5 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.36216-80-5,Benzo[d]isoxazol-3-amine,as a common compound, the synthetic route is as follows.,36216-80-5

EXAMPLE 34 2,6-DICHLORO-N-(3-BENZISOXAZOLYL)BENZAMIDE 3-Aminobenzisoxazole (2 gram), 2,6-dichlorobenzoylchloride (2 gram), and 50 ml. of toluene are heated at reflux for 16 hours. After evaporation of the solvent at reduced pressure, the resultant oily semi-solid is triturated with ether. The solid so formed is then washed with ether and water and constitutes the desired product.

As the paragraph descriping shows that 36216-80-5 is playing an increasingly important role.

Reference£º
Patent; Eli Lilly and Company; US4322429; (1982); A;,
Benzisoxazole – Wikipedia
Benzisoxazole – an overview | ScienceDirect Topics