In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis, characterization, and nonlinear optical properties of some new series of S-(5-aryl-1,3,4-oxadiazol-2-yl)-2-chloroethanethioate derivatives, published in 2019, which mentions a compound: 3326-71-4, Name is 2-Furoic hydrazide, Molecular C5H6N2O2, Electric Literature of C5H6N2O2.
In the present investigation, some novel S-(5-aryl-1,3,4-oxadiazol-2-yl)-2-chloroethanethioate I [Ar = Ph, 2-ClC6H4, 2-furanyl, 2-O2NC6H4, 3-O2NC6H4] derivatives were synthesized and their impact on optical properties was studied. The nonlinear refractive indexes of compounds I were also measured in dichloromethane via Z-scan method using a continuous wave diode-pumped laser at 532 nm wavelength. The nonlinear refractive coefficient of compounds I was obtained from 1011 m2/W order. Regarding the appropriate nonlinearity of these compounds, they could be considered good candidates for biooptical and photonic applications. All the synthesized compounds I were also evaluated for their antibacterial and antifungal activities. The bioactive assay showed that the synthetic compounds displayed variable inhibition zones against tested bacterium Escherichia coli and fungus Aspergillus fumigatus in comparison to enrofloxacin and amphotericin as reference drugs, which are normally used for treating such infections. Synthesized compounds were characterized by elemental anal. and various spectroscopic methods including FTIR, 1H NMR, 13C NMR and UV-Vis techniques.
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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics