Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 37443-42-8, is researched, SMILESS is O=C(C1OCCC1)OC, Molecular C6H10O3Journal, Article, Lipids called Antitumor activity of SRI 62-834, a cyclic ether analog of ET-18-OCH3, Author is Houlihan, William J.; Lee, Mark L.; Munder, Paul G.; Nemecek, Georgina M.; Handley, Dean A.; Winslow, Christine M.; Happy, John; Jaeggi, Christian, the main research direction is SRI 62834 preparation antitumor; blood platelet aggregation inhibitor SRI 62834; tatrahydrofuran ether phospholipid analog preparation antitumor.Related Products of 37443-42-8.
SRI 62-834 (I), an analog of the antitumor agent ET-18-OCH3 in which the O atom at C atom 2 was incorporated into a 5-membered heterocycle, was prepared and exhibited good cytotoxicity in vitro against a variety of tumor cell lines and was as effective as Et-18-OCH3 given orally to mice with Meth A sarcomas. SRI 62-834 inhibited platelet-derived growth factor, possibly at the receptor level, and platelet-activating factor at the receptor level.
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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics