The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Methyl tetrahydrofuran-2-carboxylate, is researched, Molecular C6H10O3, CAS is 37443-42-8, about A Powerful Chiral Phosphoric Acid Catalyst for Enantioselective Mukaiyama-Mannich Reactions, the main research direction is imine ketene acetal chiral phosphoric acid enantioselective Mukaiyama Mannich; amino carboxylic ester stereoselective preparation quaternary stereogenic center; chiral phosphoric acid preparation enantioselective diastereoselective Mukaiyama Mannich catalyst; Brønsted acids; Mukaiyama-Mannich reactions; asymmetric catalysis; chiral phosphoric acids; quaternary stereogenic centers.Category: benzisoxazole.
A new BINOL-derived chiral phosphoric acid bearing 2,4,6-trimethyl-3,5-dinitrophenyl substituents at the 3,3′-positions was developed. The utility of this chiral phosphoric acid is demonstrated by a highly enantioselective (ee up to >99 %) and diastereoselective (syn/anti up to >99:1) asym. Mukaiyama-Mannich reaction of imines with a wide range of ketene silyl acetals. Moreover, this method was successfully applied to the construction of vicinal tertiary and quaternary stereogenic centers with excellent diastereo- and enantioselectivity. Significantly, BINOL-derived N-triflyl phosphoramide constitutes a complementary catalyst system that allows the title reaction to be applied to more challenging imines without an N-(2-hydroxyphenyl) moiety.
Here is a brief introduction to this compound(37443-42-8)Category: benzisoxazole, if you want to know about other compounds related to this compound(37443-42-8), you can read my other articles.
Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics