Chemical Research Letters, May 2021. In an article, author is COHEN, LJ, once mentioned the application of 25383-99-7, Name is Sodium 2-((2-(stearoyloxy)propanoyl)oxy)propanoate, molecular formula is C24H43NaO6, molecular weight is 450.5844, MDL number is MFCD00152806, category is benzisoxazole. Now introduce a scientific discovery about this category, Safety of Sodium 2-((2-(stearoyloxy)propanoyl)oxy)propanoate.
Risperidone, a benzisoxazole derivative, is a novel antipsychotic agent that has an extremely strong binding affinity for serotonin 5-HT2 receptors, a strong binding affinity for dopamine D2 receptors, and a high affinity for alpha1- and alpha2-adrenergic receptors and histamine H-1 receptors. Its affinity for serotonin receptors is approximately 200 times greater than that of haloperidol, and its dopamine antagonistic potency is comparable to that of haloperidol. Its major metabolite, 9-hydroxyrisperidone, has similar pharmacologic activity, and thus the parent compound and metabolite form the active antipsychotic moiety Clinical trials demonstrate that risperidone is an effective antipsychotic agent that improves negative as well as positive symptoms of schizophrenia. At recommended dosages, the frequency of extrapyramidal side effects is no greater than that seen with placebo. The drug appears to be an advance in the treatment of psychoses.
If you are hungry for even more, make sure to check my other article about 25383-99-7, Safety of Sodium 2-((2-(stearoyloxy)propanoyl)oxy)propanoate.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics