《New synthesis of 1,2-benzisoxazole derivatives》 was written by Kalkote, Uttam R.; Goswami, Das D.. Computed Properties of C7H4BrNO2 And the article was included in Australian Journal of Chemistry on August 31 ,1977. The article conveys some information:
N-Phenylsalicylohydroxamic acids (I, R = H, Cl, Br, I) were treated with SOCl2 in the presence of pyridine in anhydrous ether at 0° to give II (via III). IV (R3 = H, OH, Me; R2 = H, Me, Cl, Br, etc.) were similarly treated to give V. In addition to this study using 5-Bromobenzo[d]isoxazol-3(2H)-one, there are many other studies that have used 5-Bromobenzo[d]isoxazol-3(2H)-one(cas: 65685-50-9Computed Properties of C7H4BrNO2) was used in this study.
5-Bromobenzo[d]isoxazol-3(2H)-one(cas: 65685-50-9) belongs to benzisoxazole.Computed Properties of C7H4BrNO2The benzisoxazole analogs represent one of the privileged structures in medicinal chemistry and there has been an increasing number of studies on benzisoxazole-containing compounds. The unique benzisoxazole scaffold also exhibits an impressive potential as antimicrobial, anticancer, anti-inflammatory, anti-glycation agents and so on.
Referemce:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics