New discoveries in chemical research and development in 2021.As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 526-83-0, Name is 2,3-Dihydroxysuccinic acid, SMILES is O=C(O)C(O)C(O)C(O)=O, in an article , author is GARCIA, G, once mentioned of 526-83-0, HPLC of Formula: https://www.ambeed.com/products/526-83-0.html.
Risperidone, a benzisoxazole derivative, was recently approved by the FDA for the management of psychotic disorders. It joins clozapine as the second antipsychotic agent to become available that possesses both dopaminergic and serotoninergic blocking activities. Risperidone has been shown to improve the positive and negative symptoms of schizophrenia in clinical trials. The drug can be used as a first-line agent and trials are currently being conducted to establish its benefit in treatment-refractory patients. Risperidone is associated with a low incidence of extrapyramidal symptoms, has not been associated with tardive dyskinesia, and does not require hematological monitoring. The availability of risperidone represents progress not only in the pharmacotherapy of schizophrenia, but also in the understanding of the pathophysiology of this disorder.
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Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics