In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called A simple and sensitive fluorescent sensor platform for Al3+ sensing in aqueous media and monitoring through combined PET and ESIPT mechanisms: practical applications in drinking water and bio-imaging, published in 2020-07-31, which mentions a compound: 3326-71-4, mainly applied to fluorescent sensor aluminum bioimging, Name: 2-Furoic hydrazide.
In this study, a novel hydrazide-based compound, (E)-N′-(5-(benzo[d]thiazol-2-yl)-2-hydroxybenzylidene)furan-2-carbohydrazide (probe BOTH, I) was designed, characterized and prepared as a fluorogenic “”turn-on”” sensor for monitoring Al3+ in near-perfect aqueous media. All emission and absorbance spectral studies were performed in HEPES/DMSO (volume/volume, 99.95/0.05, pH = 7.0) media at 25 °C. The quantum yield of probe BOTH increases considerably in the presence of Al3+. Probe BOTH could sense Al3+ at a concentration as low as 6.47 nM. Probe BOTH could sense Al3+ with high sensitivity and selectivity, and a quant. correlation of R2 = 0.9887 in the Al3+ concentration range of 0.0-20.0 equivalent To evaluate the method parameters, a validation study was performed based on different anal. parameters. The formation of complex BOTH-Al3+ (2 : 1 stoichiometry) was confirmed by 1H-NMR titration and MALDI-TOF MS, as well as Job′s methods. pH-Dependent and Benesi-Hildebrand plot studies also supported this proposed sensing mechanism. Besides, the binding mechanism of Al3+ with probe BOTH was further verified by theor. studies. Moreover, probe BOTH could be used for monitoring Al3+ in living-cells and water samples.
There are many compounds similar to this compound(3326-71-4)Name: 2-Furoic hydrazide. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.
Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics