Application of 4865-84-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.4865-84-3, Name is 1,2-Benzisoxazole-3-acetic Acid, molecular formula is C9H7NO3. In a Patent£¬once mentioned of 4865-84-3
BENZISOXAZOLE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS FOR THE TREATMENT OF E.G. RESPIRATORY DISEASES, EPILEPSY AND CONVULSIONS
This invention relates to novel benzisoxazole derivatives that are found to be potent modulators of potassium channels and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels e.g. a respiratory disease, epilepsy or convulsions. X represents a subsituent selected from the group consisting of CO-NR”R””, CO-O-R”, CO-NH-S, CO-NH-SO2R”””, CO-NH-C=N, SO2-NR”R””, 2,3-dihydro-1-H-tetrazol-5-yl and [1, 2, 4]oxadiazolidin-5-one; wherein R” and R””, independently of each other, represent hydrogen or alkyl or phenyl; and R””” represents alkyl, cycloalkyl, haloalkyl or phenyl, which phenyl may optionally be substituted one or more times with substituents selected from halo, trifluoromethyl, trifluoromethoxy, cyano and nitro.
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Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics