In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Enhanced anticancer activity of half-sandwich Ru(II)-p-cymene complex bearing heterocyclic hydrazone ligand, published in 2020-09-30, which mentions a compound: 3326-71-4, mainly applied to cymene ruthenium indole hydrazone preparation crystal mol structure; anticancer half sandwich ruthenium cymene heterocyclic hydrazone complex, Safety of 2-Furoic hydrazide.
The hydrazone ligand (HL) was synthesized from furan-2-carbohydrazide and indole-3-carboxaldehyde. The reaction of [RuCl2(p-cymene)]2 with HL in the presence of sodium methoxide yielded organometallic Ru(II)-p-cymene compound of the type [RuCl(η6-p-cymene)(η2-N,O-indole hydrazone)] (1). The ligand and complex were characterized by CHN anal. and various spectroscopic tools. The piano stool (pseudo-octahedral) geometry of the complex was confirmed by single crystal x-ray diffraction. The anticancer property of the ligand and complex was investigated against A549, HeLa and MCF7 cancer cell lines. The complex exhibited superior activity against A549 and HeLa cancer cells with the IC50 values of 23.4 and 12.9μM, resp.
In some applications, this compound(3326-71-4)Safety of 2-Furoic hydrazide is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics