The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: cis-Cyclohexane-1,2-dicarboxylic acid( cas:610-09-3 ) is researched.Synthetic Route of C8H12O4.Chandramalar, A. V. M.; Lim, Y. Y.; Leong, Y. K. published the article 《The effects of cis-trans configuration of cyclohexane multi-carboxylic acids on colloidal forces in dispersions: steric, hydrophobic and bridging》 about this compound( cas:610-09-3 ) in Colloids and Surfaces, A: Physicochemical and Engineering Aspects. Keywords: configuration effect cyclohexanecarboxylic acid zirconia colloidal force; yield stress pH zirconia cyclohexanecarboxylic acid configuration effect. Let’s learn more about this compound (cas:610-09-3).
The effects of cis- and trans-1,2-, trans-1,4-cyclohexanedicarboxylic acid, 95% cis-1,3,5-cyclohexane tricarboxylic acid and cis-1,2,3,4,5,6-cyclohexanehexacarboxylic acid on the yield stress-pH behavior of concentrated ZrO2 dispersions are reported. Adsorbed cis-1,2,3,4,5,6-cyclohexanehexacarboxylic acid imparts predominantly steric interactions. It forms a steric barrier keeping the interacting particles apart. Adsorbed cis- and trans-1,2 increase the maximum yield stress and this was attributed to a hydrophobic force resulting from the part of the cyclohexane ring sticking out into the solution which is devoid of charged or hydrophilic group. Adsorbed trans-1,4 increases the maximum yield stress by ≥3-fold and its configuration favors strong bridging interaction with an adjacent particle. Predominantly, cis-1,3,5 also increases the maximum yield stress but only by 60% at the same additive concentration This was attributed to a smaller degree of bridging.
Although many compounds look similar to this compound(610-09-3)Synthetic Route of C8H12O4, numerous studies have shown that this compound(SMILES:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics