The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: cis-Cyclohexane-1,2-dicarboxylic acid(SMILESS: O=C([C@H]1[C@@H](C(O)=O)CCCC1)O,cas:610-09-3) is researched.SDS of cas: 75732-01-3. The article 《Ionization equilibria in dicarboxylic acids undergoing conformational transitions》 in relation to this compound, is published in Journal of Physical Chemistry. Let’s take a look at the latest research on this compound (cas:610-09-3).
Succinic acid and substituted succinic acids undergo conformational transitions during ionization, and these are expected to affect their ionization equilibrium The 1H NMR data on the dependence of the conformational equilibrium of succinic acid and meso-2,3-dimethylsuccinic acid on their degree of ionization are interpreted in terms of the ratio of the 2nd ionization constants of the gauche and trans isomer, K2g/K2t, and the equilibrium constant Kc for the gauche-trans transition of the unionized acid. The K2g/K2t ratios obtained for the 2 above acids are compared with theratio of the 2nd ionization constants of cis- and trans-cyclohexane-1,2-dicarboxylic acids used as model compounds in which the carboxyls are gauche and trans to each other.
This literature about this compound(610-09-3)Name: cis-Cyclohexane-1,2-dicarboxylic acidhas given us a lot of inspiration, and I hope that the research on this compound(cis-Cyclohexane-1,2-dicarboxylic acid) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics