Ring opening [3+2] cyclization of azaoxyallyl cations with benzo[d]isoxazoles: Efficient access to 2-hydroxyaryl-oxazolines was written by He, Yicheng;Pi, Chao;Wu, Yangjie;Cui, Xiuling. And the article was included in Chinese Chemical Letters in 2020.Recommanded Product: 4-Bromobenzo[d]isoxazole This article mentions the following:
A selective ring-opening [3+2]cyclization reaction of benzo[d]isoxazoles with 2-bromo-propanamides was developed. The azaoxyallyl cation intermediates were employed as C∼O 3-atom synthon to build oxa-heterocycles via the selectivity of suitable cyclization partners. This transformation provided rapid access to highly functionalized 2-hydroxyaryl-oxazolines under mild conditions and excellent regioselectivity. In the experiment, the researchers used many compounds, for example, 4-Bromobenzo[d]isoxazole (cas: 1126848-34-7Recommanded Product: 4-Bromobenzo[d]isoxazole).
4-Bromobenzo[d]isoxazole (cas: 1126848-34-7) belongs to benzisoxazole derivatives. Benzisoxazole is an aromatic organic compound containing a benzene-fused isoxazole ring structure. Its aromaticity makes it relatively stable. These include antidepressants, anti-inflammatory agents, antimalarial drugs, antipsychotics, antiviral agents, steroids, and anesthetics.Recommanded Product: 4-Bromobenzo[d]isoxazole
Referemce:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics