A modified method for the synthesis of 1,2-benzisoxazoles was written by Thakar, K. A.;Goswami, D. D.;Bhawal, B. M.. And the article was included in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry in 1977.Recommanded Product: 7-Bromo-3-methylbenzo[d]isoxazole This article mentions the following:
Thirty-five substituted 1,2-benzisoxazoles (e.g. 3-methyl-, 3,5,7-trimethyl-6-chloro-3-ethyl-, etc.) were prepared in 85-100% yields by cyclizing o-hydroxyaryl ketoxime acetates in refluxing pyridine. Some of the benzisoxazoles exhibit antifungal activity (no data). In the experiment, the researchers used many compounds, for example, 7-Bromo-3-methylbenzo[d]isoxazole (cas: 66033-75-8Recommanded Product: 7-Bromo-3-methylbenzo[d]isoxazole).
7-Bromo-3-methylbenzo[d]isoxazole (cas: 66033-75-8) belongs to benzisoxazole derivatives. Many fluorinated compounds, 1,2-benzisoxazole derivatives and various amides are currently used in the treatment of diseases. The benzisoxazole template forms the molecular backbone, possesses versatile binding properties with a frequently occurring binding motif, and provides potent and selective ligands for a range of different biological targets in medicinal chemistry.Recommanded Product: 7-Bromo-3-methylbenzo[d]isoxazole
Referemce:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics