Chemistry, like all the natural sciences, Recommanded Product: 2-Hydroxyacetic acid, begins with the direct observation of nature¡ª in this case, of matter.79-14-1, Name is 2-Hydroxyacetic acid, SMILES is O=C(O)CO, belongs to Benzisoxazole compound. In a document, author is Soman, Shubhangi S., introduce the new discover.
Synthesis of new naphthoisoxazole amide derivatives and study of their biological evaluations
A series of naphthoisoxazole amide derivatives 4a-h have been synthesized from naphthoisoxazole acetic acid 3. 2-Acetyl-1-naphthol-1 on reaction with pulverized sodium and diethyl carbonate gave 4-hydroxy naphthopyrone 2 which on Posner reaction gave naphthoisoxazole acetic acid 3. The cytotoxic activity study for inhibiting melanoma cell survival was evaluated on a series of melanoma cell lines. The anticonvulsant activity of these compounds has been evaluated in Wistar rats. A compound called 4h has been found to have anticonvulsant activity comparable to that of the standard drug phenytoin.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 79-14-1. Recommanded Product: 2-Hydroxyacetic acid.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics