Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Methyl tetrahydrofuran-2-carboxylate, is researched, Molecular C6H10O3, CAS is 37443-42-8, about Hydrogenation and esterification of α-furancarboxylic acid over Ru-Pd/γ-Al2O3 catalyst.SDS of cas: 37443-42-8.
Me tetrahydro-α-furancarboxylate was prepared by esterification and hydrogenation of α-furancarboxylic acid using Ru-Pd/γ-Al2O3 as catalyst in fixed bed microreactor by a one-step process. Under optimum conditions, the product yield reached 97.2%. The catalyst activity did not deteriorate after 400 h.
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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics