Application of 79-14-1, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 79-14-1, Name is 2-Hydroxyacetic acid, SMILES is O=C(O)CO, belongs to Benzisoxazole compound. In a article, author is Middleton, RJ, introduce new discover of the category.
Expedient synthesis of a novel class of pseudoaromatic amino acids: tetrahydroindazol-3-yl- and tetrahydrobenzisoxazol-3-ylalanine derivatives
A concise synthesis of novel homochiral aromatic amino acid surrogates comprising a tetrahydroindazole or a benzisoxazole system was developed via the acylation of a cyclic 1,3-diketone by the side-chain carboxyl functionality of either Boc-Asp-OtBu or Boc-Glu-OtBu followed by regioselective condensation with hydrazine, N-benzylhydrazine and hydroxylamine. The tetrahydroindazole nucleus was also constructed by the condensation of Boc-Asp-OtBu with the enamine, 1-pyrrolidino-1-cyclohexene followed by acid-hydrolytic treatment and reaction with hydrazines. Further functional group transformations gave N-alpha-Fmoc-protected derivatives as useful building blocks for solid-phase peptide assembly. (C) 2003 Elsevier Ltd. All rights reserved.
Application of 79-14-1, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 79-14-1.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics