The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Methyl tetrahydrofuran-2-carboxylate( cas:37443-42-8 ) is researched.SDS of cas: 37443-42-8.Ali, Rameez; Guan, Yong; Leveille, Alexandria N.; Vaughn, Elizabeth; Parelkar, Sangram; Thompson, Paul R.; Mattson, Anita E. published the article 《Synthesis and Anticancer Activity of Structure Simplified Naturally Inspired Dimeric Chromenone Derivatives》 about this compound( cas:37443-42-8 ) in European Journal of Organic Chemistry. Keywords: dimeric chromenone synthesis anticancer; tetrahydroxanthone synthesis anticancer; Cancer; Drug Design; Drug Discovery; Medicinal Chemistry; Natural Products. Let’s learn more about this compound (cas:37443-42-8).
Select dimeric chromenones exhibit low micromolar cytotoxicity toward lymphoma and leukemia cell lines, L5178Y and HL60, resp. The bioactive dimeric chromenones were identified from a focused library of structurally simplified derivatives of naturally occurring dimeric chromenones and tetrahydroxanthones that was prepared as part of this study. The simple dimeric chromenone scaffolds contain no stereogenic centers, are easily synthesized, and may be utilized as lead compounds in cancer research and drug discovery.
After consulting a lot of data, we found that this compound(37443-42-8)SDS of cas: 37443-42-8 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics