Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 627-03-2, Name is 2-Ethoxyacetic acid, SMILES is O=C(O)COCC, belongs to Benzisoxazole compound. In a document, author is Watson, TJ, introduce the new discover, Recommanded Product: 627-03-2.
Process improvements for the preparation of kilo quantities of a series of isoindoline compounds
A series of isoindoline analogues with either an indazole (HMR 2934, HMR 2651) or benzisoxazole (HMR 2543) appendage were prepared for the proposed treatment of psychiatric disorders such as obsessive compulsive disorder and attention deficit disorder. The isoindoline compounds were prepared by reduction of the corresponding phthalimides with LiAlH4. One compound was not chiral, and the other two required an enantioselective synthesis. The key step for these optically active analogues involved the coupling by an S(N)2 process of either a piperazynyl intermediate or a piperdinyl intermediate with methyl 3-benzyloxy-2-trifluoromethansulfonatopropionate. The products for these two analogues had >98% ee. Process improvements led to the multi-kilogram syntheses of each of these compounds.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 627-03-2 is helpful to your research. Recommanded Product: 627-03-2.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics