Chemistry is an experimental science, Formula: C13H16O3, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 427-49-6, Name is alpha-Cyclopentylmandelic Acid, molecular formula is C13H16O3, belongs to benzisoxazole compound. In a document, author is Yamada, H.
Effect of anti-inflammatory bowel disease drug, E3040, on urate transport in rat renal brush border membrane vesicles
To confirm the assumption that 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole (E3040) acts on urate reabsorption by inhibiting urate-anion exchange at the luminal membrane of renal tubules, we investigated the inhibitory effect of E3040 and its two conjugated metabolites on hydroxyl ion (OH-) gradient-dependent urate uptake into brush border membrane vesicles from rat renal cortex and compared it with other uricosuric agents. The order of potency was AA193 (5-chloro-7,8-dihydro-3-phenylfuro[2,3-g]-1,2-benzisoxazole-7-carboxylic acid)> benzbromarone > E3040 > probenecid > E3040 sulfate > E3040 glucuronide. Furthermore, kinetic analysis revealed that E3040 may be a competitive inhibitor of the OH- gradient-dependent uptake of urate into brush border membrane vesicles. (C) 2000 Elsevier Science B.V. All rights reserved.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 427-49-6. Formula: C13H16O3.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics