Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 503-74-2, Name is 3-Methylbutanoic acid, molecular formula is C5H10O2, belongs to benzisoxazole compound, is a common compound. In a patnet, author is Gopalsamy, Ariamala, once mentioned the new application about 503-74-2, Recommanded Product: 3-Methylbutanoic acid.
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90
Heat shock protein 90 (Hsp90) is a molecular chaperone that is responsible for activating many signaling proteins and is a promising target in tumor biology. We have identified small-molecule benzisoxazole derivatives as Hsp90 inhibitors. Crystallographic studies show that these compounds bind in the ATP binding pocket interacting with the Asp93. Structure based optimization led to the identification of potent analogues, such as 13, with good biochemical profiles.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 503-74-2. The above is the message from the blog manager. Recommanded Product: 3-Methylbutanoic acid.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics