One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Quality Control of Benzo[d]isoxazol-3-ol, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 21725-69-9, Name is Benzo[d]isoxazol-3-ol, molecular formula is C7H5NO2
Discovery and structure-activity relationships of a novel series of benzopyran-based KATP openers for urge urinary incontinence
A novel series of benzopyran derivatives were synthesized and evaluated as KATP channel openers. Structure-activity relationships were investigated around 4-position of the benzopyran nucleus. Optimization of 4-substituent with some heterocyclic rings led to compound 13b bearing a benzo[d]isoxazol-3-one moiety as a potent and selective KATP channel opener in vitro. In two anesthetized rat models of myogenic bladder overactivity, compound 13b was found to inhibit spontaneous bladder contractions.
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Reference£º
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics