Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , COA of Formula: C7H6O3, 99-06-9, Name is 3-Hydroxybenzoic acid, molecular formula is C7H6O3, belongs to Benzisoxazole compound. In a document, author is Arndt, P, introduce the new discover.
Ring-enlargement and ring-opening reactions of benzoxazole, thiazoles, and benzisoxazole by zirconocene-alkyne complexes
Zirconocene alkyne complexes Cp(2)Zr(L)(Me(3)SiC(2)R) (L = Py, THF; R = SiMe(3), tBu) react with heterocyclic compounds like benzoxazole and related thiazoles to yield ring-expanded adducts Cp(2)Zr-C(SiMe(3))=C(R)-CH=N-o-C6H4-X (1-3) and Cp(2)Zr-C(SiMe(3))=C(SiMe(3))-CH=N-C(R’)=C(R’)-X (R’ = Me, H) (4, 5) by formal C-X (X = O, S) bond cleavage and coupling with the coordinated alkyne. In the case of benzisoxazole, the alkyne is not coupled but eliminated, and with ring-enlargement of the benzisoxazole a N-bridged dimer [Cp(2)Zr-N=CH-o-C6H4-O](2) (6) is formed. The obtained complexes 1, 3, and 6 were characterized by NMR spectra and crystal structure analysis.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 99-06-9. COA of Formula: C7H6O3.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics