Wrubel, Juergen published an article on January 31 ,1980. The article was titled 《2-Substituted 5-amino-1,2-benzisoxazoles》, and you may find the article in Zeitschrift fuer Chemie.SDS of cas: 65685-50-9 The information in the text is summarized as follows:
Nitration of benzisoxazoles I (R = OH, Cl; R1 = H) gave I (R = OH, Cl; R1 = NO2), and reaction with Br or SO2Cl2 gave I (R = OH, Cl; R1 = Br, Cl). Reduction of I (R = OH, R1 = NO2) with SnCl2 gave I (R = OH, R1 = NH2), which was diazotized and coupled with aromatic amines or phenols to give the azo dyes I (R = OH, R4 = 4-Me2NC6H4N:N, 2-hydroxy-1-naphthylazo). After reading the article, we found that the author used 5-Bromobenzo[d]isoxazol-3(2H)-one(cas: 65685-50-9SDS of cas: 65685-50-9)
5-Bromobenzo[d]isoxazol-3(2H)-one(cas: 65685-50-9) belongs to benzisoxazole.SDS of cas: 65685-50-9The benzisoxazole analogs represent one of the privileged structures in medicinal chemistry and there has been an increasing number of studies on benzisoxazole-containing compounds. The unique benzisoxazole scaffold also exhibits an impressive potential as antimicrobial, anticancer, anti-inflammatory, anti-glycation agents and so on.
Referemce:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics